Paradromics Completes First Human Brain Implant Test

The race to merge brains with machines just got more interesting. Paradromics, a neurotech startup based in Austin, Texas, has officially entered the brain-computer interface (BCI) arena with its first successful human test of a brain implant device. It’s already seen as a serious rival to Elon Musk’s Neuralink.

Inside the Breakthrough: Paradromics’ First Human Test

On May 14, 2025, Paradromics temporarily inserted its Connexus brain implant into a human patient’s brain. The procedure took place at the University of Michigan, where the patient was already undergoing brain surgery for epilepsy. With the patient’s full consent, Paradromics was given the green light to insert and remove the device, all within about 10 minutes.

This was not a permanent implant. Instead, it served as a short but crucial “dress rehearsal” to make sure the device could:

Be safely inserted,
Capture real brain signals,
And be removed without complications.

The result? It was a clear success. The Connexus device successfully recorded brain activity, confirming it’s ready for more advanced trials.

What Is the Connexus Device?

The Connexus is a tiny yet powerful piece of technology, smaller than a dime. It has 420 tiny needle-like electrodes that gently enter brain tissue. These electrodes are designed to pick up signals from individual neurons, which is a major upgrade from older systems that detect only broad group activity.

Paradromics believes recording individual neuron activity is key to translating what someone wants to say, even if they can’t physically speak, into actual speech, text, or digital commands.

Why It Matters

This breakthrough could one day help people who’ve lost the ability to speak due to stroke, ALS, or spinal cord injury. Imagine being able to “speak” with your thoughts, even when your mouth no longer works. That’s the goal.

Other companies are working toward similar missions:

Neuralink uses a similar approach with high-density implants inserted into the brain.
Precision Neuroscience is testing surface-level implants (no deep brain penetration).
Synchron has developed a less invasive method using blood vessels near the brain.

However, Paradromics’ strength lies in signal clarity; the more accurate the data, the better the translation from brain to machine.

Is It Safe?

Yes, and that’s a big reason why this test matters. According to Paradromics CEO Matt Angle, doing the test during a planned surgery lowered the risk. The implant was delivered with a special device (described as an EpiPen for the brain), and it caused no harm.

What’s Next for Paradromics?

The company is gearing up to launch a full clinical trial by the end of 2025. This time, the implants will be long-term, helping paralyzed patients communicate again. In the future, Paradromics even plans to explore placing multiple implants in the brain to gather even more data.

And no, these devices don’t “read your mind.” BCIs like Connexus detect signals linked to movement intention, like trying to talk or move a hand, and turn that into output, such as speech or cursor movement.

The Bigger Picture

Brain-computer interfaces are no longer science fiction. With Paradromics joining the fight, the field is heating up, and that’s good news for innovation. While Neuralink might get the headlines, this new contender shows that competition can fast-track real, life-changing tech.

Paradromics’ first human test may have lasted just 10 minutes, but it’s a sign of a much bigger future where communication is no longer limited by the body but powered by the brain.